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Affinity of the New Cephalosporin CXA-101 to Penicillin-Binding Proteins of Pseudomonas aeruginosa

CXA-101, previously designated FR264205, is a new antipseudomonal cephalosporin. The objective of this study was to determine the penicillin-binding protein (PBP) inhibition profile of CXA-101 compared to that of ceftazidime (PBP3 inhibitor) and imipenem (PBP2 inhibitor). Killing kinetics, the induc...

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Detalhes bibliográficos
Main Authors: Moyá, Bartolomé, Zamorano, Laura, Juan, Carlos, Ge, Yigong, Oliver, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934984/
https://ncbi.nlm.nih.gov/pubmed/20547785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00296-10
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