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Liposomal Amphotericin B and Echinocandins as Monotherapy or Sequential or Concomitant Therapy in Murine Disseminated and Pulmonary Aspergillus fumigatus Infections

Monotherapy and combination therapy were compared using optimal doses of liposomal amphotericin B, micafungin, or caspofungin in Aspergillus fumigatus pulmonary and disseminated infections. Mice were challenged intravenously (2.8 × 10(4) to 5.7 × 10(4) conidia) or intranasally (5.8 × 10(7) conidia)...

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Detalhes bibliográficos
Main Authors: Olson, Jon A., George, Ancy, Constable, David, Smith, Peter, Proffitt, Richard T., Adler-Moore, Jill P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934978/
https://ncbi.nlm.nih.gov/pubmed/20606065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01554-09
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