Liposomal Amphotericin B and Echinocandins as Monotherapy or Sequential or Concomitant Therapy in Murine Disseminated and Pulmonary Aspergillus fumigatus Infections

Monotherapy and combination therapy were compared using optimal doses of liposomal amphotericin B, micafungin, or caspofungin in Aspergillus fumigatus pulmonary and disseminated infections. Mice were challenged intravenously (2.8 × 10(4) to 5.7 × 10(4) conidia) or intranasally (5.8 × 10(7) conidia)...

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Autori principali: Olson, Jon A., George, Ancy, Constable, David, Smith, Peter, Proffitt, Richard T., Adler-Moore, Jill P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934978/
https://ncbi.nlm.nih.gov/pubmed/20606065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01554-09
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