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Easy Strategy To Protect Antimicrobial Peptides from Fast Degradation in Serum
Antimicrobial peptides are promising novel peptide leads, but their low serum stability often limits their further consideration in drug development programs. Here, we describe a generally applicable strategy to stabilize peptides against serum proteases by replacing arginine residues with α-amino-3...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934954/ https://ncbi.nlm.nih.gov/pubmed/20585128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00300-10 |
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