Rho-ROCK-Myosin Signaling Meditates Membrane Type 1 Matrix Metalloproteinase-induced Cellular Aggregation of Keratinocytes

Membrane type 1-matrix metalloproteinase (MT1-MMP, MMP14), which is associated with extracellular matrix (ECM) breakdown in squamous cell carcinoma (SCC), promotes tumor formation and epithelial-mesenchymal transition. However, in this report we demonstrate that MT1-MMP, by cleaving the underlying E...

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Main Authors: Dangi-Garimella, Surabhi, Redig, Amanda J., Shields, Mario A., Siddiqui, Mohammed A., Munshi, Hidayatullah G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934700/
https://ncbi.nlm.nih.gov/pubmed/20605790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146019
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