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Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

PDAC (pancreatic ductal adenocarcinoma) is among the most deadly of human malignances. A hallmark of the disease is a pronounced collagen-rich fibrotic extracellular matrix known as the desmoplastic reaction. Intriguingly, it is precisely these areas of fibrosis in which human PDAC tumours demonstra...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Shields, Mario A., Dangi-Garimella, Surabhi, Redig, Amanda J., Munshi, Hidayatullah G.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215985/
https://ncbi.nlm.nih.gov/pubmed/22187935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111240
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