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Inactivation of Patched1 in the Mouse Limb Has Novel Inhibitory Effects on the Chondrogenic Program

The bones of the vertebrate limb form by the process of endochondral ossification, whereby limb mesenchyme condenses to form an intermediate cartilage scaffold that is then replaced by bone. Although Indian hedgehog (IHH) is known to control hypertophic differentiation of chondrocytes during this pr...

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書誌詳細
主要な著者: Bruce, Stephen J., Butterfield, Natalie C., Metzis, Vicki, Town, Liam, McGlinn, Edwina, Wicking, Carol
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934663/
https://ncbi.nlm.nih.gov/pubmed/20576618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091785
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