Llwytho...

Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic hedgehog and promoting outgrowth of the vertebrate limb

Cross-talk between the fibroblast growth factor (FGF) and Sonic Hedgehog (Shh) pathways is critical for proper patterning and growth of the developing limb bud. Here, we show that FGF dependent activation of the ETS transcription factors Etv4 and Etv5 contributes to proximal-distal limb outgrowth. S...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mao, Junhao, McGlinn, Edwina, Huang, Peng, Tabin, Clifford J., McMahon, Andrew P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164484/
https://ncbi.nlm.nih.gov/pubmed/19386268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.005
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