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Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic hedgehog and promoting outgrowth of the vertebrate limb
Cross-talk between the fibroblast growth factor (FGF) and Sonic Hedgehog (Shh) pathways is critical for proper patterning and growth of the developing limb bud. Here, we show that FGF dependent activation of the ETS transcription factors Etv4 and Etv5 contributes to proximal-distal limb outgrowth. S...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164484/ https://ncbi.nlm.nih.gov/pubmed/19386268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.005 |
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