Expression of Y53A-Actin in Dictyostelium Disrupts the Cytoskeleton and Inhibits Intracellular and Intercellular Chemotactic Signaling

We showed previously that phosphorylation of Tyr(53), or its mutation to Ala, inhibits actin polymerization in vitro with formation of aggregates of short filaments, and that expression of Y53A-actin in Dictyostelium blocks differentiation and development at the mound stage (Liu, X., Shu, S., Hong,...

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Bibliografiske detaljer
Main Authors: Shu, Shi, Liu, Xiong, Kriebel, Paul W., Hong, Myoung-Soon, Daniels, Mathew P., Parent, Carole A., Korn, Edward D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934639/
https://ncbi.nlm.nih.gov/pubmed/20610381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116277
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