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Expression of Y53A-Actin in Dictyostelium Disrupts the Cytoskeleton and Inhibits Intracellular and Intercellular Chemotactic Signaling

We showed previously that phosphorylation of Tyr(53), or its mutation to Ala, inhibits actin polymerization in vitro with formation of aggregates of short filaments, and that expression of Y53A-actin in Dictyostelium blocks differentiation and development at the mound stage (Liu, X., Shu, S., Hong,...

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Detalhes bibliográficos
Main Authors: Shu, Shi, Liu, Xiong, Kriebel, Paul W., Hong, Myoung-Soon, Daniels, Mathew P., Parent, Carole A., Korn, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934639/
https://ncbi.nlm.nih.gov/pubmed/20610381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116277
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