Expression of Y53A-Actin in Dictyostelium Disrupts the Cytoskeleton and Inhibits Intracellular and Intercellular Chemotactic Signaling

We showed previously that phosphorylation of Tyr(53), or its mutation to Ala, inhibits actin polymerization in vitro with formation of aggregates of short filaments, and that expression of Y53A-actin in Dictyostelium blocks differentiation and development at the mound stage (Liu, X., Shu, S., Hong,...

Full description

Saved in:
Bibliographic Details
Main Authors: Shu, Shi, Liu, Xiong, Kriebel, Paul W., Hong, Myoung-Soon, Daniels, Mathew P., Parent, Carole A., Korn, Edward D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934639/
https://ncbi.nlm.nih.gov/pubmed/20610381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116277
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items