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Daptomycin, a Bacterial Lipopeptide Synthesized by a Nonribosomal Machinery

Daptomycin (Cubicin®) is a branched cyclic lipopeptide antibiotic of nonribosomal origin and the prototype of the acidic lipopeptide family. It was approved in 2003 for the nontopical treatment of skin structure infections caused by Gram-positive pathogens, including methicillin-resistant Staphyloco...

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Bibliographic Details
Main Authors: Robbel, Lars, Marahiel, Mohamed A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934615/
https://ncbi.nlm.nih.gov/pubmed/20522545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.128181
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