Plasma ceramides are altered in MCI and predict cognitive decline and hippocampal volume loss

BACKGROUND: A blood-based biomarker of Alzheimer disease (AD) would be superior to CSF and neuroimaging measures in terms of cost, invasiveness and feasibility for repeated measures. We previously reported blood ceramides varied in relation to timing of memory impairment in a population-based study....

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Autors principals: Mielke, Michelle M., Haughey, Norman J., Bandaru, Veera Venkata Ratnam, Schech, Steven, Carrick, Richard, Carlson, Michelle C., Mori, Susumu, Miller, Michael I., Ceritoglu, Can, Brown, Timothy, Albert, Marilyn, Lyketsos, Constantine G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933928/
https://ncbi.nlm.nih.gov/pubmed/20813340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2010.03.014
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