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Plasma ceramides are altered in MCI and predict cognitive decline and hippocampal volume loss

BACKGROUND: A blood-based biomarker of Alzheimer disease (AD) would be superior to CSF and neuroimaging measures in terms of cost, invasiveness and feasibility for repeated measures. We previously reported blood ceramides varied in relation to timing of memory impairment in a population-based study....

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Detalhes bibliográficos
Main Authors: Mielke, Michelle M., Haughey, Norman J., Bandaru, Veera Venkata Ratnam, Schech, Steven, Carrick, Richard, Carlson, Michelle C., Mori, Susumu, Miller, Michael I., Ceritoglu, Can, Brown, Timothy, Albert, Marilyn, Lyketsos, Constantine G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933928/
https://ncbi.nlm.nih.gov/pubmed/20813340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2010.03.014
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