Histone Sin mutations promote nucleosome traversal and histone displacement by RNA polymerase II

Nucleosome traversal by RNA polymerase II (pol II) and recovery of chromatin structure after transcription are essential for proper gene expression. In this paper we show that nucleosomes assembled with Sin mutant histones present a much weaker barrier to traversal by pol II and are less likely to s...

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Bibliographic Details
Main Authors: Hsieh, Fu-Kai, Fisher, Michael, Újvári, Andrea, Studitsky, Vasily M, Luse, Donal S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933865/
https://ncbi.nlm.nih.gov/pubmed/20706221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.113
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