Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

In eukaryotes, only a fraction of replication origins fire at each S phase. Local histone acetylation was proposed to control firing efficiency of origins, but conflicting results were obtained. We report that local histone acetylation does not reflect origin efficiencies along the adenosine monopho...

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Detalhes bibliográficos
Main Authors: Gay, Sophie, Lachages, Anne-Marie, Millot, Gael A, Courbet, Sylvain, Letessier, Anne, Debatisse, Michelle, Brison, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933864/
https://ncbi.nlm.nih.gov/pubmed/20671737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.112
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