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Photo-cytotoxic trans diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers
The photocytotoxicity of a series of anticancer trans-dihydroxido [Pt(N(3))(2)(OH)(2)(NH(3))(X)] (X = alkyl or aryl amine) platinum(IV) diazido complexes has been examined and the influence of cis-trans isomerism investigated. A series of photoactivatable Pt(IV)-azido complexes has been synthesized:...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933822/ https://ncbi.nlm.nih.gov/pubmed/19994893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900372p |
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