SAP Protein Dependent Natural Killer T-Like Cells Regulate the Development of CD8(+) T Cells with Innate Lymphocyte Characteristics

CD8(+) T cells are selected via low affinity interaction with MHC class I molecules on thymic epithelial cells (TECs). However, compromised T cell receptor signaling was proposed to force CD8(+) T cell selection on hematopoietic cells through a SLAM-associated protein (SAP)-dependent mechanism simil...

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Hlavní autoři: Verykokakis, Mihalis, Boos, Markus D., Bendelac, Albert, Kee, Barbara L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933745/
https://ncbi.nlm.nih.gov/pubmed/20674402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.07.013
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