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SAP Protein Dependent Natural Killer T-Like Cells Regulate the Development of CD8(+) T Cells with Innate Lymphocyte Characteristics
CD8(+) T cells are selected via low affinity interaction with MHC class I molecules on thymic epithelial cells (TECs). However, compromised T cell receptor signaling was proposed to force CD8(+) T cell selection on hematopoietic cells through a SLAM-associated protein (SAP)-dependent mechanism simil...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933745/ https://ncbi.nlm.nih.gov/pubmed/20674402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.07.013 |
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