Reactive Astrocytes Protect Melanoma Cells from Chemotherapy by Sequestering Intracellular Calcium through Gap Junction Communication Channels

Brain metastases are highly resistant to chemotherapy. Metastatic tumor cells are known to exploit the host microenvironment for their growth and survival. We report here that melanoma brain metastases are surrounded and infiltrated by activated astrocytes, and we hypothesized that these astrocytes...

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מידע ביבליוגרפי
Main Authors: Lin, Qingtang, Balasubramanian, Krishnakumar, Fan, Dominic, Kim, Sun-Jin, Guo, Lixia, Wang, Hua, Bar-Eli, Menashe, Aldape, Kenneth D, Fidler, Isaiah J
פורמט: Artigo
שפה:Inglês
יצא לאור: Neoplasia Press Inc. 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933695/
https://ncbi.nlm.nih.gov/pubmed/20824051
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