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Synthesis and evaluation of new spacers for use as dsDNA endcaps

A series of aliphatic and aromatic spacer molecules designed to cap the ends of DNA duplexes have been synthesized. The spacers were converted into dimethoxytrityl protected phosphoramidites as synthons for oligonucleotides synthesis. The effect of the spacers on the stability of short DNA duplexes...

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Bibliografische gegevens
Hoofdauteurs: Ng, Pei-Sze, Laing, Brian M., Balasundarum, Ganesan, Pingle, Maneesh, Friedman, Alan, Bergstrom, Donald E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933660/
https://ncbi.nlm.nih.gov/pubmed/20715857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100202y
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