Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells

Bcl-3 is an atypical member of the inhibitor of NF-kappa B family of proteins since it can function as a coactivator of transcription. Although this oncogene was described in leukemia, it is overexpressed in a number of solid tumors as well. The oncogenic potential of Bcl-3 has been associated with...

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Bibliografiske detaljer
Main Authors: Zamora, Ruben, Espinosa, Magali, Ceballos-Cancino, Gisela, Segura, Blanca, Maldonado, Vilma, Melendez-Zajgla, Jorge
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933622/
https://ncbi.nlm.nih.gov/pubmed/20731879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-223
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