miR‐10b expression in breast cancer stem cells supports self‐renewal through negative PTEN regulation and sustained AKT activation

Cancer stem cells (CSCs) are linked to metastasis. Moreover, a discrete group of miRNAs (metastamiRs) has been shown to promote metastasis. Accordingly, we propose that miRNAs that function as metastatic promoters may influence the CSC phenotype. To study this issue, we compared the expression of 35...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Rep
Prif Awduron: Bahena‐Ocampo, Ivan, Espinosa, Magali, Ceballos‐Cancino, Gisela, Lizarraga, Floria, Campos‐Arroyo, Denise, Schwarz, Angela, Maldonado, Vilma, Melendez‐Zajgla, Jorge
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341522/
https://ncbi.nlm.nih.gov/pubmed/27113763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540678
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