miR‐10b expression in breast cancer stem cells supports self‐renewal through negative PTEN regulation and sustained AKT activation

Cancer stem cells (CSCs) are linked to metastasis. Moreover, a discrete group of miRNAs (metastamiRs) has been shown to promote metastasis. Accordingly, we propose that miRNAs that function as metastatic promoters may influence the CSC phenotype. To study this issue, we compared the expression of 35...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Bahena‐Ocampo, Ivan, Espinosa, Magali, Ceballos‐Cancino, Gisela, Lizarraga, Floria, Campos‐Arroyo, Denise, Schwarz, Angela, Maldonado, Vilma, Melendez‐Zajgla, Jorge
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341522/
https://ncbi.nlm.nih.gov/pubmed/27113763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540678
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