A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus

BACKGROUND: Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is the preferred approach for prevention of H5N1 infection. Seasonal influenza virus infection has been reported to provide heterosubtypic immunity agains...

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Autors principals: Chang, Haiyan, Huang, Chaoyang, Wu, Jian, Fang, Fang, Zhang, Wenjie, Wang, Fuyan, Chen, Ze
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933593/
https://ncbi.nlm.nih.gov/pubmed/20727202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-197
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