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Intranasal Immunization of Mice to Avoid Interference of Maternal Antibody against H5N1 Infection

Maternally-derived antibodies (MDAs) can protect offspring against influenza virus infection but may also inhibit active immune responses. To overcome MDA- mediated inhibition, active immunization of offspring with an inactivated H5N1 whole-virion vaccine under the influence of MDAs was explored in...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zhang, Fenghua, Peng, Bo, Chang, Haiyan, Zhang, Ran, Lu, Fangguo, Wang, Fuyan, Fang, Fang, Chen, Ze
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900595/
https://ncbi.nlm.nih.gov/pubmed/27280297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157041
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