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Epithelial Ablation of Bcl-X(L) Increases Sensitivity to Oxygen without Disrupting Lung Development

Recent studies indicate that the antiapoptotic Bcl-X(L), one of five isoforms expressed by the Bcl-X gene, protects a variety of cell lines exposed to hyperoxia. However, its role in lung development and protection against oxidative stress in vivo is not known. Here, we show Bcl-X(L) is the predomin...

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Detalhes bibliográficos
Main Authors: Staversky, Rhonda J., Vitiello, Peter F., Yee, Min, Callahan, Linda M., Dean, David A., O'Reilly, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933553/
https://ncbi.nlm.nih.gov/pubmed/19880821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0165OC
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