Fas Ligand Expression on T Cells Is Sufficient to Prevent Prolonged Airway Inflammation in a Murine Model of Asthma

Our previous studies revealed that, in a murine model of asthma, mice that received Fas-deficient T cells developed a prolonged phase of airway inflammation, mucus production, and airway hyperreactivity that failed to resolve even 6 weeks after the last challenge. To investigate how Fas–Fas ligand (...

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Main Authors: Tong, Jiankun, Clay, Bryan S., Ferreira, Caroline M., Bandukwala, Hozefa S., Moore, Tamson V., Blaine, Kelly M., Williams, Jesse W., Hoffman, Lisa M., Hamann, Kimm J., Shilling, Rebecca A., Weinstock, Joel V., Sperling, Anne I.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933550/
https://ncbi.nlm.nih.gov/pubmed/19855087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0454OC
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