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Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

Resistance to chemotherapy in ovarian cancer is poorly understood. Evolutionary models of cancer predict that, following treatment, resistance emerges either due to outgrowth of an intrinsically resistant sub-clone, or evolves in residual disease under the selective pressure of treatment. To investi...

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Detaylı Bibliyografya
Asıl Yazarlar: Cooke, Susanna L, Ng, Charlotte KY, Melnyk, Nataliya, Garcia, Maria J, Hardcastle, Tom, Temple, Jillian, Langdon, Simon, Huntsman, David, Brenton, James D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933510/
https://ncbi.nlm.nih.gov/pubmed/20581869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.245
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