Converging Evidence for Efficacy from Parallel EphB4 Targeted Approaches in Ovarian Carcinoma

EphB4 is a transmembrane receptor tyrosine kinase that plays an important role in neural plasticity and angiogenesis. EphB4 is overexpressed in ovarian cancer and is predictive of poor clinical outcome. However, the biological significance of EphB4 in ovarian cancer is not known and is the focus of...

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Hlavní autoři: Spannuth, Whitney A., Mangala, Lingegowda S., Stone, Rebecca L., Carroll, Amy R., Nishimura, Masato, Shahzad, Mian M.K., Lee, Sun-Joo, Moreno-Smith, Myrthala, Nick, Alpa M., Liu, Ren, Jennings, Nicholas B., Lin, Yvonne G., Merritt, William M., Coleman, Robert L., Vivas-Mejia, Pablo E., Zhou, Yue, Krasnoperov, V., Lopez-Berestein, Gabriel, Gill, Parkash S., Sood, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933364/
https://ncbi.nlm.nih.gov/pubmed/20682653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0200
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