Converging Evidence for Efficacy from Parallel EphB4 Targeted Approaches in Ovarian Carcinoma

EphB4 is a transmembrane receptor tyrosine kinase that plays an important role in neural plasticity and angiogenesis. EphB4 is overexpressed in ovarian cancer and is predictive of poor clinical outcome. However, the biological significance of EphB4 in ovarian cancer is not known and is the focus of...

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Main Authors: Spannuth, Whitney A., Mangala, Lingegowda S., Stone, Rebecca L., Carroll, Amy R., Nishimura, Masato, Shahzad, Mian M.K., Lee, Sun-Joo, Moreno-Smith, Myrthala, Nick, Alpa M., Liu, Ren, Jennings, Nicholas B., Lin, Yvonne G., Merritt, William M., Coleman, Robert L., Vivas-Mejia, Pablo E., Zhou, Yue, Krasnoperov, V., Lopez-Berestein, Gabriel, Gill, Parkash S., Sood, Anil K.
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933364/
https://ncbi.nlm.nih.gov/pubmed/20682653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0200
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