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The Role of the Thymus in Tolerance
The thymus serves as the central organ of immunologic self-non-self discrimination. Thymocytes undergo both positive and negative selection resulting in T cells with a broad range of reactivity to foreign antigens but a lack of reactivity to self-antigens. The thymus is also the source of a subset o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933313/ https://ncbi.nlm.nih.gov/pubmed/20555306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181e7e54f |
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