β(1) Integrin Inhibitory Antibody Induces Apoptosis of Breast Cancer Cells, Inhibits Growth, and Distinguishes Malignant from Normal Phenotype in Three Dimensional Cultures and In vivo

Current therapeutic approaches to cancer are designed to target molecules that contribute to malignant behavior but leave normal tissues intact. β(1) integrin is a candidate target well known for mediating cell-extracellular matrix (ECM) interactions that influence diverse cellular functions; its ab...

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Main Authors: Park, Catherine C., Zhang, Hui, Pallavicini, Maria, Gray, Joe W., Baehner, Frederick, Park, Chong J., Bissell, Mina J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933188/
https://ncbi.nlm.nih.gov/pubmed/16452209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-3071
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