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Three-dimensional culture models of normal and malignant breast epithelial cells

Extracellular matrix is a key regulator of normal homeostasis and tissue phenotype1. Important signals are lost when cells are cultured ex vivo on two-dimensional plastic substrata. Many of these crucial microenvironmental cues may be restored using three-dimensional (3D) cultures of laminin-rich ex...

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Autores principales: Lee, Genee Y, Kenny, Paraic A, Lee, Eva H, Bissell, Mina J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933182/
https://ncbi.nlm.nih.gov/pubmed/17396127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1015
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