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FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A

Building reliable structural models of G protein-coupled receptors (GPCRs) is a difficult task due to the paucity of suitable templates, low sequence identity, and the wide variety of ligand specificities within the superfamily. Template-based modeling is known to be the most successful method for p...

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Hlavní autoři: Michino, Mayako, Chen, Jianhan, Stevens, Raymond C., Brooks, Charles L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933064/
https://ncbi.nlm.nih.gov/pubmed/20544957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22731
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