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Cell death in mammalian cell culture: molecular mechanisms and cell line engineering strategies

Cell death is a fundamentally important problem in cell lines used by the biopharmaceutical industry. Environmental stress, which can result from nutrient depletion, by-product accumulation and chemical agents, activates through signalling cascades regulators that promote death. The best known key r...

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Podrobná bibliografie
Hlavní autoři: Krampe, Britta, Al-Rubeai, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932912/
https://ncbi.nlm.nih.gov/pubmed/20502964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9274-0
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