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Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice
The efficacy of a stabilized chemical analog of double-stranded ribonucleic acid (RNA), PIKA, as prophylaxis against infection with 5 different influenza A virus subtypes, including the 2009 swine-origin pandemic H1N1 virus, was evaluated in mice. Intranasal treatment with PIKA resulted in significa...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932846/ https://ncbi.nlm.nih.gov/pubmed/20667572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.008 |
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