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Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice

The efficacy of a stabilized chemical analog of double-stranded ribonucleic acid (RNA), PIKA, as prophylaxis against infection with 5 different influenza A virus subtypes, including the 2009 swine-origin pandemic H1N1 virus, was evaluated in mice. Intranasal treatment with PIKA resulted in significa...

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Bibliografische gegevens
Hoofdauteurs: Lau, Yuk-Fai, Tang, Lay-Hoon, Ooi, Eng-Eong, Subbarao, Kanta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932846/
https://ncbi.nlm.nih.gov/pubmed/20667572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.008
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