PolyADP-Ribosylation Is Required for Pronuclear Fusion during Postfertilization in Mice

BACKGROUND: During fertilization, pronuclear envelope breakdown (PNEB) is followed by the mingling of male and female genomes. Dynamic chromatin and protein rearrangements require posttranslational modification (PTM) for the postfertilization development. METHODOLOGY/PRINCIPAL FINDINGS: Inhibition o...

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Detalhes bibliográficos
Main Authors: Osada, Tomoharu, Ogino, Hideki, Hino, Toshiaki, Ichinose, Sachiyo, Nakamura, Kenji, Omori, Akira, Noce, Toshiaki, Masutani, Mitsuko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932744/
https://ncbi.nlm.nih.gov/pubmed/20824066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012526
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