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DNA Clasping by Mycobacterial HU: The C-Terminal Region of HupB Mediates Increased Specificity of DNA Binding

BACKGROUND: HU a small, basic, histone like protein is a major component of the bacterial nucleoid. E. coli has two subunits of HU coded by hupA and hupB genes whereas Mycobacterium tuberculosis (Mtb) has only one subunit of HU coded by ORF Rv2986c (hupB gene). One noticeable feature regarding Mtb H...

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Autori principali: Kumar, Sandeep, Sardesai, Abhijit A., Basu, Debashree, Muniyappa, Kalappagowda, Hasnain, Seyed E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932737/
https://ncbi.nlm.nih.gov/pubmed/20824060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012551
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