DNA Clasping by Mycobacterial HU: The C-Terminal Region of HupB Mediates Increased Specificity of DNA Binding

BACKGROUND: HU a small, basic, histone like protein is a major component of the bacterial nucleoid. E. coli has two subunits of HU coded by hupA and hupB genes whereas Mycobacterium tuberculosis (Mtb) has only one subunit of HU coded by ORF Rv2986c (hupB gene). One noticeable feature regarding Mtb H...

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Asıl Yazarlar: Kumar, Sandeep, Sardesai, Abhijit A., Basu, Debashree, Muniyappa, Kalappagowda, Hasnain, Seyed E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932737/
https://ncbi.nlm.nih.gov/pubmed/20824060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012551
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