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Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production

The hepatitis C virus (HCV) p7 protein is critical for virus production and an attractive antiviral target. p7 is an ion channel when reconstituted in artificial lipid bilayers, but channel function has not been demonstrated in vivo and it is unknown whether p7 channel activity plays a critical role...

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Detalhes bibliográficos
Main Authors: Wozniak, Ann L., Griffin, Stephen, Rowlands, David, Harris, Mark, Yi, MinKyung, Lemon, Stanley M., Weinman, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932723/
https://ncbi.nlm.nih.gov/pubmed/20824094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001087
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