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TLR4-Dependent and -Independent Regulation of Hepatic Cytochrome P450 in Mice with Chemically-Induced Inflammatory Bowel Disease

The transcription and protein expression of many cytochrome P450 (P450) genes are down-regulated in animal models of inflammation and infection. We determined previously that hepatic P450 mRNAs are selectively regulated in a mouse model of enteropathogenic bacterial infection, and that this regulati...

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Autors principals: Chaluvadi, Madhusudana R., Nyagode, Beatrice A., Kinloch, Ryan D., Morgan, Edward T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932663/
https://ncbi.nlm.nih.gov/pubmed/19027721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.10.029
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