Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing

We describe the integration of microfluidic selection with high-throughput DNA sequencing technology for rapid and efficient discovery of nucleic acid aptamers. The Quantitative Selection of Aptamers through Sequencing method tracks the copy number and enrichment-fold of more than 10 million individ...

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Detalles Bibliográficos
Autores principales: Cho, Minseon, Xiao, Yi, Nie, Jeff, Stewart, Ron, Csordas, Andrew T., Oh, Seung Soo, Thomson, James A., Soh, H. Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932614/
https://ncbi.nlm.nih.gov/pubmed/20705898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009331107
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