Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells

Quantitative mass spectrometry was used to identify hormone-dependent signaling pathways in renal medullary thick ascending limb (mTAL) cells via phosphoproteomic analysis. Active transport of NaCl across the mTAL epithelium is accelerated by hormones that increase cAMP levels (vasopressin, glucagon...

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Detalhes bibliográficos
Main Authors: Gunaratne, Ruwan, Braucht, Drew W. W., Rinschen, Markus M., Chou, Chung-Lin, Hoffert, Jason D., Pisitkun, Trairak, Knepper, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932563/
https://ncbi.nlm.nih.gov/pubmed/20713729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007424107
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