Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells

Quantitative mass spectrometry was used to identify hormone-dependent signaling pathways in renal medullary thick ascending limb (mTAL) cells via phosphoproteomic analysis. Active transport of NaCl across the mTAL epithelium is accelerated by hormones that increase cAMP levels (vasopressin, glucagon...

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Autori principali: Gunaratne, Ruwan, Braucht, Drew W. W., Rinschen, Markus M., Chou, Chung-Lin, Hoffert, Jason D., Pisitkun, Trairak, Knepper, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932563/
https://ncbi.nlm.nih.gov/pubmed/20713729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007424107
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