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Single-molecule derivation of salt dependent base-pair free energies in DNA

Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in thermal denaturation experiments, which depend on several assumptions. Here we report measurements o...

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Detalhes bibliográficos
Main Authors: Huguet, Josep M., Bizarro, Cristiano V., Forns, Núria, Smith, Steven B., Bustamante, Carlos, Ritort, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932562/
https://ncbi.nlm.nih.gov/pubmed/20716688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001454107
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