Neuropathogenic SIVsmmFGb Genetic Diversity and Selection-Induced Tissue-Specific Compartmentalization During Chronic Infection and Temporal Evolution of Viral Genes in Lymphoid Tissues and Regions of the Central Nervous System

SIVsmmFGb is a lentivirus swarm that induces neuropathology in over 90% of infected pigtailed macaques and reliably models central nervous system HIV infection in people. We have previously studied SIVsmmFGb genetic diversity and compartmentalization during acute infection, but little is understood...

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Bibliographische Detailangaben
Hauptverfasser: Reeve, Aaron B., Pearce, Nicholas C., Patel, Kalpana, Augustus, Katherine V., Novembre, Francis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2010
Schlagworte:
Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932553/
https://ncbi.nlm.nih.gov/pubmed/20518690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0168
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