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Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells

PURPOSE: Increasing evidence suggests that tear hyperosmolarity is a central mechanism causing ocular surface inflammation and damage in dry eye disease. Mapracorat (BOL-303242-X) is a novel glucocorticoid receptor agonist currently under clinical evaluation for use in the treatment of dry eye disea...

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書目詳細資料
Main Authors: Cavet, Megan E., Harrington, Karen L., Ward, Keith W., Zhang, Jin-Zhong
格式: Artigo
語言:Inglês
出版: Molecular Vision 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932489/
https://ncbi.nlm.nih.gov/pubmed/20824100
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