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Designed Fluorescent Probes Reveal Interactions between Amyloid-β(1–40) Peptides and G(M1) Gangliosides in Micelles and Lipid Vesicles

A hallmark of the common Alzheimer's disease (AD) is the pathological conversion of its amphiphatic amyloid-β (Aβ) peptide into neurotoxic aggregates. In AD patients, these aggregates are often found to be tightly associated with neuronal G(M1) ganglioside lipids, suggesting an involvement of G...

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Detalhes bibliográficos
Main Authors: Mikhalyov, I., Olofsson, A., Gröbner, G., Johansson, L.B.-Å.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931726/
https://ncbi.nlm.nih.gov/pubmed/20816063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.043
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