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Designed Fluorescent Probes Reveal Interactions between Amyloid-β(1–40) Peptides and G(M1) Gangliosides in Micelles and Lipid Vesicles
A hallmark of the common Alzheimer's disease (AD) is the pathological conversion of its amphiphatic amyloid-β (Aβ) peptide into neurotoxic aggregates. In AD patients, these aggregates are often found to be tightly associated with neuronal G(M1) ganglioside lipids, suggesting an involvement of G...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931726/ https://ncbi.nlm.nih.gov/pubmed/20816063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.043 |
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