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GM(1) Ganglioside Inhibits β‐Amyloid Oligomerization Induced by Sphingomyelin
β‐Amyloid (Aβ) oligomers are neurotoxic and implicated in Alzheimer's disease. Neuronal plasma membranes may mediate formation of Aβ oligomers in vivo. Membrane components sphingomyelin and GM(1) have been shown to promote aggregation of Aβ; however, these studies were performed under extreme,...
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| Опубликовано в: : | Angew Chem Int Ed Engl |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089616/ https://ncbi.nlm.nih.gov/pubmed/27295499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603178 |
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