Drug- and cue-induced reinstatement of cannabinoid-seeking behaviour in male and female rats: influence of ovarian hormones

BACKGROUND AND PURPOSE: Animal and human studies have shown that sex and hormones are key factors in modulating addiction. Previously, we have demonstrated that self-administration of the cannabinoid CB(1) receptor agonist WIN55,212-2 (WIN; 12.5 µg·kg(−1) per infusion) is dependent on sex, intact fe...

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Autors principals: Fattore, L, Spano, MS, Altea, S, Fadda, P, Fratta, W
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931571/
https://ncbi.nlm.nih.gov/pubmed/20590575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00734.x
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