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Chemogenetic Inactivation of Orbitofrontal Cortex Decreases Cue-Induced Reinstatement of Ethanol and Sucrose Seeking in Male and Female Wistar Rats

BACKGROUND: The orbitofrontal cortex (OFC) encodes internal representations of outcomes and subjective value to facilitate flexible reward-seeking. OFC activation is associated with drug seeking in both human subjects and animal models. OFC plays a role in alcohol use, but studies in animal models h...

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Pubblicato in:Alcohol Clin Exp Res
Autori principali: Hernandez, John S., Binette, Annalise N., Rahman, Taryn, Tarantino, Jeffrey D., Moorman, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722059/
https://ncbi.nlm.nih.gov/pubmed/32628778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14407
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