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TGF-β, IL-6, IL-17 and CTGF direct multiple pathologies of chronic cardiac allograft rejection

Cardiac transplantation is an effective treatment for heart failure refractive to therapy. Although immunosuppressive therapeutics have increased first year survival rates, chronic rejection remains a significant barrier to long-term graft survival. Chronic rejection manifests as patchy interstitial...

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Détails bibliographiques
Auteurs principaux: Booth, Adam J, Bishop, D Keith
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931419/
https://ncbi.nlm.nih.gov/pubmed/20636005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.10.33
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