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Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle

Contractile activation in striated muscles requires a Ca(2+) reservoir of large capacity inside the sarcoplasmic reticulum (SR), presumably the protein calsequestrin. The buffering power of calsequestrin in vitro has a paradoxical dependence on [Ca(2+)] that should be valuable for function. Here, we...

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Autores principales: Royer, Leandro, Sztretye, Monika, Manno, Carlo, Pouvreau, Sandrine, Zhou, Jingsong, Knollmann, Bjorn C., Protasi, Feliciano, Allen, Paul D., Ríos, Eduardo
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931149/
https://ncbi.nlm.nih.gov/pubmed/20713548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010454
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